Identifying Critical Binder Attributes to Facilitate Binder Selection for Efficient Formulation Development in a Continuous Twin

Concise overview of the critical binder attributes influencing the binder effectiveness for a poorly and highly soluble formulation

Identifying Critical Binder Attributes to Facilitate Binder Selection for Efficient Formulation Development in a Continuous Twin Screw Wet Granulation Process

9. February 2021

The suitability of pharmaceutical binders for continuous twin-screw wet granulation was investigated as the pharmaceutical industry is undergoing a switch...

Material tracking in a continuous direct capsule-filling process via residence time distribution measurements

29. January 2021

Continuous production of pharmaceuticals requires traceability from the raw material to the final dosage form. With that regard, understanding the...

Continuous blending monitored and feedback controlled by machine vision-based PAT tool

24. January 2021

In a continuous powder blending process machine vision is utilized as a Process Analytical Technology (PAT) tool. While near-infrared (NIR)...

Starch Products as Candidate Excipients in a Continuous Direct Compression Line

10. January 2021

Direct compression (DC) remains the most preferred technique to produce tablets, and its effectiveness is directly influenced by raw material...

$Roll Compactor with In-line laser diffraction to measure granule size$

Implementing Feedback Granule Size Control in a Continuous Dry Granulation Line Using Controlled Impeller Speed of the Granulation Unit, Compaction Force and Gap Width

22. December 2020

In continuous manufacturing of pharmaceuticals, dry granulation is of interest because of its large throughput capacity and energy efficiency. In...

Integrated Twin-Screw Wet Granulation, Continuous Vibrational Fluid Drying and Milling: A fully continuous powder to granule line

21. December 2020

Highly homogeneous low-dose (50 µg) tablets were produced incorporating perfectly free-flowing granules prepared by a fully integrated Continuous Manufacturing (CM)...

Experimental setup for the continuous blending and tableting of the CFC-filtered ASA

Towards better understanding of the influence of process parameters in roll compaction/ dry granulation on throughput, ribbon microhardness and granule failure load

16. November 2020

A key quality attribute for solid oral dosage forms is their hardness and ability to withstand breaking or grinding. If...

Continuous manufacturing

Identifying Critical Binder Attributes to Facilitate Binder Selection for Efficient Formulation Development in a Continuous Twin Screw Wet Granulation Process

Material tracking in a continuous direct capsule-filling process via residence time distribution measurements

Continuous blending monitored and feedback controlled by machine vision-based PAT tool

Starch Products as Candidate Excipients in a Continuous Direct Compression Line

Implementing Feedback Granule Size Control in a Continuous Dry Granulation Line Using Controlled Impeller Speed of the Granulation Unit, Compaction Force and Gap Width

Integrated Twin-Screw Wet Granulation, Continuous Vibrational Fluid Drying and Milling: A fully continuous powder to granule line

Development of integrated continuous pharmaceutical technologies

Directly compressible hydroxypropyl methylcellulose (HPMC) to support continuous manufacturing

Process Design of Continuous Powder Blending Using Residence Time Distribution and Feeding Models

Towards better understanding of the influence of process parameters in roll compaction/ dry granulation on throughput, ribbon microhardness and granule failure load

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