Successful Formulation Window for the design of pharmaceutical tablets with required mechanical properties

3. January 2024

Abstract Pharmaceutical tablet formulations combine the active ingredient with processing aids and functional components. This paper evaluates compressibility based predictive...

Revolutionary Advancements in Fast Dissolving Tablets: An In-Depth Exploration

7. December 2023

ABSTRACT A novel drug delivery system plays a pivotal role in enhancing patient adherence to medication regimens. Among these innovative...

VITAMIN E – Direct Compression with PROSOLV 730

28. November 2023

Aim of the study Solid dose formulations of Vitamin E, an oily active ingredient, are typically produced as soft-gel capsules...

Effect of magnesium stearate solid lipid nanoparticles as a lubricant on the properties of tablets by direct compression

24. November 2023

Abstract This study discusses the lubricant properties of magnesium stearate solid lipid nanoparticles (MgSt-SLN) and their effect on the tabletability,...

Exploring Applications of Plant-Derived Polymers in Fused Deposition Modeling of Oral Pharmaceutical Tablets

20. November 2023

Introduction Additive manufacturing or 3D printing technology refers to the fabrication of three-dimensional objects from computer-aided designs (CAD) by adding...

Lubricant Sensitivity of Direct Compression Grades of Lactose in Continuous and Batch Tableting Process

17. November 2023

Abstract Modern pharmaceutical manufacturing based on Quality by Design and digitalisation is revolutionising the pharmaceutical industry. Continuous processes are promoted...

The influence of directly compressible fillers/diluents on selected compact properties and drug dissolution: a case study of rivaroxaban

23. October 2023

Introduction Direct compression represents a favorable tablet manufacturing method. However, obtaining satisfactory mechanical properties of the compacts and drug dissolution...

Fig. 1. Aspirin direct compressible tablets

Study of Microcrystalline Cellulose as a Substitute of Magnesium Stearate Towards Functionality of Lubricant in Aspirin Formulation

12. October 2023

Abstract In pharmaceutical industries, magnesium stearate is used as a lubricating agent. It is frequently used in the solid dosage...

Fig. 5 Schematic representation of particle size based theoretical surface coverage by assuming that each lubricant particle occupies the hexagonal shaped surface according to its median particle size.

Investigation of Dispersion Kinetics of Particulate Lubricants and their Effect on the Mechanical Strength of MCC Tablets

11. October 2023

Abstract Introduction Tablets are commonly produced by internally adding particulate lubricants, which are known to possibly lower the mechanical strength...

Fig. 1 SEM images of F-Melt type C (A), F-Melt type M (B), Ludifash (C), Pharmaburst 500 (D), Prosolv ODT G2 (E), and authors mix (F).

Investigating the Impact of Co-processed Excipients on the Formulation of Bromhexine Hydrochloride Orally Disintegrating Tablets (ODTs)

2. October 2023

Abstract Purpose Orodispersible tablets (orally disintegrating tablets, ODTs) have been used in pharmacotherapy for over 20 years since they overcome the...

Lubricant

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→ Introduction to Lubricants as Pharmaceutical Excipients