All4Nutra
All4Nutra
New BENEO webinar: From powder to DC oral solid dosage forms
galenIQ™ is a sweet-tasting water soluble filler binder derived from sugar beet. It is available in several different morphological forms which are suitable for the formulation and manufacture of oral solid dosage forms including tablets, effervescents, medicated lozenges and powder blends for sachets and stickpacks.
In this webinar we will discuss the powder characteristics of the galenIQ™ direct compression grades and how these grades can be used conveniently to make oral solid dosage forms.
galenIQ™ is the pharmaceutical grade of BENEO’s ISOMALT, a disaccharide alcohol derived from beet sugar. Its source material is the main reason why galenIQ™ has a sweetness and taste profile that is very close to sucrose. With its well-balanced sweetness, the filler-binder has no significant off-tastes or aftertaste. galenIQ™ reduces the bitter taste of active pharmaceutical ingredients (APIs), masks the unpleasant taste of ingredients such as plant extracts and contributes to a palatable pleasant taste profile and mouthfeel in the final pharmaceutical or nutraceutical product. galenIQ™ is the optimal choice for the formulation of solid as well as liquid oral applications and is particularly useful in paediatric formulations.
A recent comparative study[1] has shown that galenIQ™ is able to considerably suppress the bitterness of a quinine hydrochloride solution. In comparison to maltitol, mannitol and sucrose, the addition of galenIQ™ (grade 721) in concentrations as low as 3 to 6% w/w led to a significantly higher reduction in bitterness. It is therefore not surprising that galenIQ™ is the excipient of choice where taste matters.
[1] Source: Luhn, Habara, Cepok, Black and Bernard, PharmaChem, 9-10, 2014
