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Comprecel® SMCC – Silicified Microcrystalline Cellulose
by Mingtai Chemical
Comprecel® SMCC
Mingtai Chemical is a leading global manufacturer dedicated to the development and production of high-quality, functional excipients for the pharmaceutical, nutraceutical, and food industries . With a legacy spanning over 50 years, the company has built a reputation for excellence in quality consistency and manufacturing efficiency.
Mingtai Chemical Key Product Categories
Mingtai Chemical specializes in high-performance excipients designed to optimize drug formulation and production processes. Our core product portfolio includes:
- Comprecel® (Microcrystalline Cellulose): A flagship product line widely utilized as a binder and filler in solid dosage forms.
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Comprecel® SMCC (Silicified Microcrystalline Cellulose): A high-functionality excipient designed to provide superior flow and compressibility.
- Disolcel® (Croscarmellose Sodium): An essential disintegrant used to ensure efficient drug release in pharmaceutical and nutraceutical applications. Non-GMO grade is available.
- Neocel® (Colloidal Microcrystalline Cellulose): A co-processed stabilizer of MCC and NaCMC that act as a high-performance suspending agent and stabilizer for aqueous systems.
Learn more about Comprecel® SMCC (Silicified Microcrystalline Cellulose) here:
Mingtai is one of the leading excipient manufacturer in the world for decades. We are renowned for our stable and high-quality products worldwide. Our new product Comprecel® SMCC is not an exception regarding stability, and quality.
Product Description
Silicified Microcrystalline Cellulose(SMCC) is an integrated particle combined with 98% Microcrystalline Cellulose and 2% colloidal silicon dioxide. By co-processing technology, colloidal silicon dioxide is uniformly distributed on surface of MCC particle. Comprecel® SMCC is a highly functional ingredient that solve complex formulation problems and simplify manufacturing process
Products
Superior Benefits
- Improved Compactibility
- Enhanced Flow
- Less sensitive for lubrication
- Dust-reduced Handling in production
Improved Compactibility
With SMCC in formulation, less excipient is required and lower compression force is needed to manufacture robust tablets.
The chart shows if we divide hardness increase rate by SMCC, physical blending with MCC and colloidal silicon dioxide, the hardiness increase rate will be 30-50% higher than using M102 only.
Enhanced Flow
The apparent difference in flowability performance between MCC only, MCC and colloidal silicon dioxide physical blending and SMCC is shown in the chart.
Uniform dispersion of colloidal silicon dioxide on MCC particles gives SMCC superior flowability without compromising compactibility.
Less sensitivity to lubrication
When lubricant is added in formulation, the hardness will decrease as mixed time of lubricant and other ingredient goes by. However with SMCC added, the rate of hardness decrease will decline.
The data shows the hardness decrease rate of formulation with SMCC is lower than traditional MCC.
See the product overview on Comprecel® SMCC:
(click the picture to download the flyer)
Source: Mingtai Chemical, brochure Comprecel® SMCC
Request a sample or more information on Mingtai Chemical excipients here:
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