LipoGalen™ 144 – A new Base for Ovules and Suppositories

LipoGalen™ 144 – The innovative new base for ovules and suppositories

Novelty

• Crystallizes in one stable modification in contrast to triglycerides
• New base is a “hydrophilic lipid”, thus
  • Hydrophilic character allows for stable water uptake which is unusual for lipid-based excipients
  • Lipidic character leads to better adhesion to the mucous membrane, resulting in potentially longer contact time

Case Study: LipoGalen™ 144 – A new base for lactic acid ovules

A case study in structured development and usability validation of a gynecological medical device

Goal

• Development of a medical device with LipoGalen™ and lactic acid.
• It shall be comparable to a reference product.

Focus

• Formulation development with LipoGalen™ and lactic acid comparable to the commercial benchmark.
• Evaluation of the application in a usability study to demonstrate comparable user experience and identify additional benefits.

The Product

• IOI lactic acid ovules are a medical device designed to support and maintain a healthy vaginal microbiome
• Their innovative formulation enables a potentially longer contact time and thus a longer-lasting release of lactic acid

Advantages

• Natural. Effective. Long-lasting. Vegan.
• Next-generation vaginal ovules: Petroleum- and PEG-free, patented base*, slow melting behavior
• High demand (CAGR: 4.6%): Meets growing consumer preference for natural intimate care products

Product development strategy

Systematic evaluation identified a safe, stable, and user-friendly device

Green light for usability study with ovules made with LipoGalen™ 144

Head-to-head usability study compared the new device against the commercial benchmark

Usability study – Objective:

• Collect data to demonstrate the comparability of IOI Oleo lactic acid ovules with the reference product

Study methods:

• Structured questionnaires to be answered after the application of the ovules

Usability Study – Results

• Safety: no device-related issues
• Users reported that the new device felt pleasant and comfortable
• Comparable to reference product
• Additional benefit: new product may also be suitable for daytime use because of improved mucoadhesive properties

See the full brochure as PDF on LipoGalen™ 144 here:

(click the picture to download the brochure)

Source: IOI Oleo, poster LipoGalen™ 144, CPHI-2025_LipoGalen_ovules_WEB.pdf

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