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Startseite » News » LipoGalen™ – IOI Oleo´s new family of functional lipid-based excipients

LipoGalen™ – IOI Oleo´s new family of functional lipid-based excipients

20. November 2025
LipoGalen™ – Our new family of functional lipid-based excipients

LipoGalen™ – Our new family of functional lipid-based excipients

CPhI Frankfurt 2025 Review

IOI Oleo´s  innovative polyglycerol esters now have a name – We’re thrilled to introduce LipoGalen™ as the brand name for our new family of Functional Lipid-Based Excipients.

In the last IOI newsletter, we announced the launch of our new family of functional, lipid-based excipients, the polyglycerol esters. After intensive and dedicated research and development plus countless hours of brainstorming sessions, IOI Oleo GmbH finally unveils something truly special:

LipoGalen™

will be the name of our new brand, which will be making its debut at CPHI Frankfurt.

This launch marks a major milestone for us, and we couldn’t be prouder to share it with you. LipoGalen™ was born out of a deep understanding of the evolving challenges in pharmaceutical formulation. In contrast to common triglycerides, it crystallizes in one stable modification and does not show any polymorphism.

LipoGalen™ offers a versatile, forward-thinking platform designed to empower innovation across a wide range of applications:

  • Rectal and vaginal dosage forms: A novel lipid base that offers new possibilities in the formulation development of such products, with advantages for patients.

  • Controlled-release tablets: Matrix systems that allow precise control over drug-release profiles throughout the shelf-life, because of the superior properties of LipoGalen™ over traditional triglycerides.
  • Solubilization and bioavailability enhancement: Perfect for hot melt extrusion, improving the performance of poorly soluble APIs, while offering the chance of working at reduced processing temperatures compared to the established polymers in this field of application.

  • Taste masking: Effective via hot melt coating, helping improve patient compliance.

  • Lubrication for tableting: Optimized for continuous manufacturing processes.
  • Dermal formulations: Free from paraffins, supporting clean-label, skin-friendly solutions.
  • Advanced delivery systems: Suitable for lipid nanoparticles and nano-emulsions, including inhalation therapies.

  • 3D-printing: Compatible with melt extrusion techniques for personalized medicine and cutting-edge dosage forms.

Let’s shape the future of pharmaceutical development — together.

Continue reading here

Source: IOI Oleo, Dr. Thomas Rillmann, website LipoGalen™ – Our new family of functional lipid-based excipients, https://www.ioioleo.de/en/news/lipogalen-our-new-family-of-functional-lipid-based-excipients/


Enjoy the IOI Oleo interview on the new product family at the CPHI Frankfurt 2025:


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Figure 1: Proportion of poorly soluble active ingredients in approved preparations and in the development pipeline (Source: Hauss, D. J. (2023). Lipid-based drug delivery systems for poorly water-soluble drugs: Advances and challenges. Advanced Drug Delivery Reviews, Elsevier)

Polyglycerol esters – the new generation of functional lipids for pharmaceutical applications

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      • ADM
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      • Budenheim
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