Quality by Design (QbD)

In industrial practice, the development of pharmaceutical dry granulation processes typically involves time- and resource-intensive multivariate experiments. These experiments are...

High shear wet granulation (HSWG), as a widely used granulation technology, has been studied extensively. However, for the HSWG of...

Microcrystalline cellulose (MCC) is one of the most popular cellulose derivatives in the pharmaceutical industry. Thanks to its outstanding tabletability,...

In this study, we developed a control strategy for a drug product prepared by high-shear wet granulation and roller compaction...

The pandemic we are experiencing made us realize the impact and need for medication in patients' lives. These, in turn,...

Quality by design (QbD) can also contribute to design, manufacturing, and producing highly finished goods. To better explain the manufacturing...

In present work, a film forming gel (FFG) was developed through ingenious amalgamation of polymers: Pullulan, Terminalia catappa and Carbopol®971P ® for...

During wet granulation, the sample can be exposed to considerable mechanical effects, moisture content and elevated temperatures, and during high-shear...

In the manufacturing of pharmaceutical Oral Solid Dosage (OSD) forms, Particle Size Distribution (PSD) and Tensile Strength (TS) are common...

In this paper we present a thorough description of the digital twin development for a continuous pharmaceutical powder blending process...