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Abstract Johanson (1965) developed a one-dimensional model for the stress acting on the powder in between the rolls of a...
From minitablets to stick-packs: BENEO’s filler-binder galenIQ™ makes it easy for manufacturers to meet a growing need for convenient paediatric...
The relevance of the polymorphic form, particle size, and processing of mannitol for the mechanical properties of solid oral dosage...
Objective The aim of this study was to use an alternative granulation technique, solventless roll compaction, and to investigate the...
Abstract Continuous Manufacturing Technology continues to gain importance in pharmaceutical manufacturing. Although traditional processes like direct compression, roller compaction, or...
Dry granulation via roller compaction is increasingly being used as granulation method for the production of oral solid dosage forms....
Developing a robust roller compaction process can be challenging, due to the diversity in process parameters and material properties of...
Roll compaction/ dry granulation is gaining importance. Numerous papers have been published and many attempts to model the process are available in...
Granule size distribution (GSD) is one of the critical quality attributes in the roller compaction (RC) process. Determination of GSD...
Isomalt is a polyol derived from sucrose. Advantages of this excipient are its sweet taste, which is supposed to allow...
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