BASF

Excipients play an important role in formulating a dosage form. In recent years drug formulation scientists have recognized that single...

Poor oral bioavailability of mesalamine (Mes) is due to extensive metabolism in the intestinal epithelial cells in addition to the...

Short freeze-drying cycles for biopharmaceuticals are desirable. Formulations containing an amorphous disaccharide, such as sucrose, are prone to collapse upon...

From a patient-centric perspective, oromucosal drug delivery is highly attractive due to the ease of administration without the need of...

Soluplus® is a commercially available graft amphipathic copolymer consisting of polyvinyl caprolactam, polyvinyl acetate, and polyethyleneglycol (13% PEG 6000/57% vinyl...

Cilnidipine (CLD) is extensively used in the treatment of hypertension; however, it has extremely low solubility which limits its clinical...

In this study, the abilities of hydroxypropyl methylcellulose (HPMC) and methylcellulose (MC) as nonionic surfactants to improve the dissolution rate...

Drug hydrolytic degradation, caused by atmospheric and inherent humidity, significantly reduces the therapeutic effect of pharmaceutical solid dosages. Moisture barrier...

Film coating is applied to a wide variety of pharmaceutical products, including tablets, pellets, granules, capsules, powders and crystals. Pharmaexcipients...

Mefenamic acid, a BCS class II drug, displays high permeability and low solubility, thereby exhibiting a poor dissolution profile. Hence...