PMC Isochem

As a high number of active pharmaceutical ingredients (APIs) under development belong to BCS classes II and IV, the need...

Abstract Developing safe and effective formulations for the geriatric and pediatric population is a challenging task due to issues of...

In this research, Camptothecin-loaded mixed micelles (CPT-MMs) were formulated by combining Soluplus®, a novel amphiphilic excipient, with D-alpha-tocopheryl polyethylene glycol...

Producing amorphous solid dispersions (ASDs) by hot-melt extrusion (HME) is favorable from an economic and ecological perspective but also limited...

In this study, Enzalutamide (ENZ) loaded Poly Lactic-co-Glycolic Acid (PLGA) nanoparticles coated with polysarcosine and d-α-Tocopheryl polyethylene glycol 1000 succinate (TPGS)...

Abstract Cerebral ischemia represents a particular condition among neurological diseases due to its high frequency, high associated mortality, and the...

A dry powder inhaled liposomal azithromycin formulation was developed for the treatment of chronic respiratory diseases such as cystic fibrosis...

This study was focused on one particular case of hot-melt coating with trilaurin – a solid medium-chain monoacid triglyceride. The...

Osteoarthritis is the most common chronic joint disease and a major health care concern due to the lack of efficient...

The widely used vitamin-E based amphiphilic material, tocopheryl polyethylene glycol succinate (TPGS) is further improvised as redox-sensitive thiolated TPGS (TPGS-SH),...