PMC Isochem

Anthracycline antibiotics, namely, doxorubicin (DOX) and daunorubicin, are among the most widely used anticancer therapies, yet are notoriously associated with...

The proposed research work aims to develop hyaluronic acid conjugated tacrolimus-loaded nanostructured lipid carriers (HYA-TAC-loaded-SA-NLCs) to improve the release rate...

Abstract Objectives The present study is intended to develop a shell-core tablet using a hot melt extrusion (HME)-based dual-nozzle fused...

As a high number of active pharmaceutical ingredients (APIs) under development belong to BCS classes II and IV, the need...

Abstract Developing safe and effective formulations for the geriatric and pediatric population is a challenging task due to issues of...

In this research, Camptothecin-loaded mixed micelles (CPT-MMs) were formulated by combining Soluplus®, a novel amphiphilic excipient, with D-alpha-tocopheryl polyethylene glycol...

Producing amorphous solid dispersions (ASDs) by hot-melt extrusion (HME) is favorable from an economic and ecological perspective but also limited...

In this study, Enzalutamide (ENZ) loaded Poly Lactic-co-Glycolic Acid (PLGA) nanoparticles coated with polysarcosine and d-α-Tocopheryl polyethylene glycol 1000 succinate (TPGS)...

Abstract Cerebral ischemia represents a particular condition among neurological diseases due to its high frequency, high associated mortality, and the...

A dry powder inhaled liposomal azithromycin formulation was developed for the treatment of chronic respiratory diseases such as cystic fibrosis...