PMC Isochem

This study was focused on one particular case of hot-melt coating with trilaurin – a solid medium-chain monoacid triglyceride. The...

Osteoarthritis is the most common chronic joint disease and a major health care concern due to the lack of efficient...

The widely used vitamin-E based amphiphilic material, tocopheryl polyethylene glycol succinate (TPGS) is further improvised as redox-sensitive thiolated TPGS (TPGS-SH),...

Abstract Purpose Treating posterior segment diseases presents significant challenges because of the intricate anatomical and physiological barriers within the eye...

Erastin is the most classical small molecular ferroptosis inducer but its clinical application is hindered due to its poor solubility....

The upper airways represent the point of entrance from where Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection spreads to...

Due to their unique characteristics, microemulsions (ME) represent one of the most promising delivery systems which can conquer poor ocular...

Abstract Sorafenib (SFN) is an anticancer multi-kinase inhibitor with great therapeutic potential. However, SFN has low aqueous solubility, which limits...

Abstract Vaccination has emerged as the most effective strategy to confront infectious diseases, among which is leishmaniasis, that threat public...

Abstract Drug delivery via the oral route has always been challenging for poorly soluble drugs. Acid-induced hydrolysis, enzymatic degradation, and...