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CBD Overview
Topical Delivery of Cannabinoids
Providing texture and stability
A short video to explain how Gattefossé all-in-one emulsifiers help simplify topical formulations and enable to obtain a wide range of sensorial textures
Tefose® 63: widely used oil-in-water emulsifier
Gelot™ 64: oil-in-water emulsifier, preferred for high…
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Pharmacokinetic Investigation of Synthetic Cannabidiol Oral Formulations in Healthy Volunteers
Recent advances in the research of medicinal cannabis has placed the non-intoxicating cannabinoid cannabidiol (CBD) at the front of many investigations. The reasons behind this popularity is the compound’s therapeutic properties, alongside a safe profile of administration lacking addictive…
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Full-Spectrum Cannabis Extract Microdepots Support Controlled Release of Multiple Phytocannabinoids…
The therapeutic effect of the Cannabis plant largely depends on the presence and specific ratio of a spectrum of phytocannabinoids. While prescription of medicinal Cannabis for various conditions constantly grows, its consumption is mostly limited to oral or respiratory pathways, impeding its…
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Is cannabidiol a scheduled controlled substance? Origin makes the difference
Cannabidiol (CBD) is the main cannabinoid naturally occurring in hemp. It has recently attracted the attention of the scientific community because of its numerous pharmacological activities. However, its legal status changes depending on whether it is chemically synthesized or extracted from the…
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MEDICINAL CANNABIS AND THE GACP/GMP JUNGLE
Medicinal Cannabis can support various treatments in reducing side effects and symptoms, such as nausea and pain. Medicinal Cannabis, however, has to comply to GMP requirements as any medicinal substance or product has. Navigate the requirements together with Avanti Europe.
THE RESTRICTIONS AROUND…
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CBD loaded microparticles as a potential formulation to improve paclitaxel and doxorubicin-based…
Cannabidiol (CBD) has emerged as a potential agent for breast cancer management.
In this work, the potential use of cannabidiol in solution (CBDsol) and encapsulated in polymeric microparticles when combined with paclitaxel (PTX) and doxorubicin (DOX) in breast cancer treatment has been evaluated…
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Development of a Novel Nanoemulsion Formulation to Improve Intestinal Absorption of Cannabidiol
Cannabidiol (CBD) is highly lipophilic, and its oral bioavailability is known to be very low in humans. In this study, we developed a novel nanoemulsion preparation of CBD (CBD-NE) to improve the poor solubility and absorption of CBD. The pharmacokinetic profiles of CBD in rats were evaluated after…
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Cannabidiol—transdermal delivery and anti-inflammatory effect in a murine model
Cannabidiol (CBD) and the potential benefit is the current hot topic. Just found this publication by the group of Elka Touítou Hebrew University of Jerusalem from 2003. She will hold at this years PBP Worldmeeting the presentation: "Delivery of cannabinoids to and across the skin". It is interesting…
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Challenges and Opportunities in Preclinical Research of Synthetic Cannabinoids for Pain Therapy
Cannabis has been used in pain management since 2900 BC. In the 20th century, synthetic cannabinoids began to emerge, thus opening the way for improved efficacy. The search for new forms of synthetic cannabinoids continues and, as such, the aim of this review is to provide a comprehensive tool for…
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Cannabinoids in pharmaceutical development
The development of cannabinoids in the pharmaceutical industry has exploded over the past few years. With the gradual liberation of regulations worldwide that govern cannabis and its pharmaceutical derivatives for medicinal use, this week PharmaCompass leveraged its Technology Prospector tool to…
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