Lipid Excipients for Drug Delivery - Gattefossé's new product catalogue

Gattefossé’s product catalogue has been refreshed. See the updates:

? Inclusion of their excipients launched in 2021: Emulfree® Duo, Gelucire® 59/14 and Labrafac™ MC60.

? Update of US monograph names for Capryol® 90, Capryol® PGMC and Labrafac™ MC60

? Highlighting excipients with Chinese bundling review

Functional lipid excipients

Our lipid excipients are manufactured using vegetable oils (including corn, apricot kernel or coconut oil), a wide array of plant-derived fatty acids, and alcohols such as fatty alcohols, polyethylene glycol (PEG), propylene glycol (PG) and polyglycerol.

Three reactions are commonly utilized to manufacture our excipients:

esterification, a reaction between an acid and an alcohol leading to an ester and water
transesterification, a reaction between an ester and an alcohol to produce a different ester and alcohol
interesterification, a reaction between esters to produce new esters

Depending on the used raw materials, these reactions enable the manufacture of solid, semi-solid, or liquid excipients. The fatty-acid chain length and composition in terms of fatty alcohols and mono-, di- and triglycerides, impact the end-product physicochemical and functional properties. Our oleochemists are able to develop functional pharmaceutical excipients having targeted properties through the selection of raw materials, the design and control of the synthesis reaction.

Download the new catalogue here

About Gattefossé

Since 1880, Gattefossé develops innovative lipid excipients for oral solubilization, bioavailability enhancement, sustained release, lubrication, API protection and taste-masking. We provide solubilizers and skin penetration enhancers, emulsifiers and consistency agents for improved topical and transdermal formulations. Gattefossé has also dedicated ranges for the veterinary and the nutraceutical markets. Every product is designed with utmost attention to safety, quality, and performance consistency. As part of Gattefossé offer, technical and regulatory support is provided by fully trained experts to accelerate customers drug development programs.