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      • Artificial Sweeteners
      • Carbohydrates
      • Cellulose
      • Cellulose Esters
      • Cellulose Ethers
      • CMC and Croscarmellose Sodium
      • Converted Starch
      • Dried Starch
      • Microcrystalline Cellulose
      • Modified Starch
      • Starch
      • Sugars
      • Sugar Alcohols
    • Petrochemicals
      • Acrylic Polymers
      • Glycols
      • Mineral Hydrocarbons
      • Mineral Oils
      • Mineral Waxes
      • Petrolatum
      • Polyethylene Glycol (PEG)
      • Povidones
      • Propylene Glycol
      • Other Petrochemical Excipients
    • Oleochemicals
      • Fatty Alcohols
      • Glycerin
      • Mineral Stearates
      • Pharmaceutical Oils
      • Other Oleochemical Excipients
    • Proteins
  • Applications
    • 3D Printing – Drug Carrier
      • 3D Printing
      • Binder
      • Coating
      • Colour / Color
      • Coating Systems and Additives
      • Controlled Release Excipient
      • DC excipient
      • Disintegrant / Superdisintergrant
      • Drug Carrier
    • Emulsifier – Glidant
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      • Excipient for Inhalation
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Startseite » News » Parteck® TA (Calcium Carbonate): Enhanced opacity with ideal particle properties

Parteck® TA (Calcium Carbonate): Enhanced opacity with ideal particle properties

2. June 2023
Parteck® TA (Calcium Carbonate): Enhanced opacity with ideal particle properties

Parteck® TA (Calcium Carbonate): Enhanced opacity with ideal particle properties

Titanium dioxide is extensively used in solid dosage forms as an opacifier and colorant. Due to regulatory developments and restrictions by authorities, formulators are increasingly interested in titanium dioxide-free solutions for both dietary supplements and medicinal products. Uniform colored and white coatings applied to tablets not only have an aesthetic function but also improve patient compliance.

Parteck® TA excipient – Mercks titanium dioxide alternative – has been developed to address the need for an appealing white finish that does not use titanium dioxide. Its unique morphology and designed particle size distribution ensures enhanced opacity, even for challenging pre-colored tablets cores.

This mineral pigment performs excellently when used in HPMC- and PVA-based film coatings for immediate release tablets, thereby allowing higher pigment concentrations while maintaining high process efficiency. An ideal choice of film coating agent is Parteck® COAT (art. 141517), a PVA-based excipient that is even able to achieve increased opacity compared to standard HPMC-containing formulations.

Parteck® TA helps you to achieve a level of covering and whiteness comparable to TiO2-containing film coatings without affecting your tablets’ performance, making it a suitable alternative to titanium dioxide.

Parteck® TA (Calcium Carbonate)

  • High process efficiency due to lower viscosity of the spraying liquid
  • Enables an appealing and uniform tablet appearance
  • Enhanced opacity due to tailored particle size distribution and unique morphology

General description

With formulation challenges in mind, we have used particle engineering technologies to develop functional excipients specifically for solid dosage forms. The products in our Parteck® portfolio feature unique particle properties tailored for excellent performance in tableting processes, for specific drug delivery technologies, or for solubility enhancement.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Due to regulatory developments, there is an increasing interest in titanium dioxide-free solutions for the coloring of solid dosage forms. Parteck® TA – our titanium dioxide alternative – is a mineral and nature-identical pigment specifically developed for the use in tablet film coatings. It helps to achieve a level of covering and whiteness comparable to titanium dioxide film coatings without affecting your tablets’ performance. The enhanced opacity is ensured by its unique morphology and designed particle size distribution

Benefits of Parteck® TA

  • Mineral and nature-identical pigment
  • GRAS, and compliant with Ph Eur, BP and USP
  • Our Emprove® documentation facilitates qualification, risk assessment, and process optimization
  • Excellent compatibility with HPMC and PVA film coatings (including our Parteck® COAT)
  • High process efficiency due to lower viscosity of the spraying liquid
  • Enables an appealing and uniform tablet appearance
  • Enhanced opacity due to tailored particle size distribution and unique morphology

Download also the Parteck® TA (Calcium Carbonate) SDS PDF here Parteck TA_SDS

Source: Merck, Website https://www.sigmaaldrich.com/DE/en/campaigns/parteck-ta

 

MORE ON MERCK EXCIPIENTS

Do you need more information or a sample of Parteck® TA (Calcium Carbonate) by Merck?

Tags: excipientsformulation

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      • CMC and Croscarmellose Sodium
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    • Petrochemicals
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      • Glycols
      • Mineral Hydrocarbons
      • Mineral Oils
      • Mineral Waxes
      • Petrolatum
      • Polyethylene Glycol (PEG)
      • Povidones
      • Propylene Glycol
      • Other Petrochemical Excipients
    • Oleochemicals
      • Fatty Alcohols
      • Glycerin
      • Mineral Stearates
      • Pharmaceutical Oils
      • Other Oleochemical Excipients
    • Proteins
  • Applications
    • 3D Printing – Drug Carrier
      • 3D Printing
      • Binder
      • Coating
      • Colour / Color
      • Coating Systems and Additives
      • Controlled Release Excipient
      • DC excipient
      • Disintegrant / Superdisintergrant
      • Drug Carrier
    • Emulsifier – Glidant
      • Emulsifier
      • Excipient for Inhalation
      • Filler
      • Film former
      • Flavour / Flavor
      • Glidant
    • Lubricant – Preservative
      • Lubricant
      • Nanotechnology
      • Orally Dissolving Technology Excipient
      • Pellet
      • Plasticizer
      • Preservative
    • Solubilizer – Viscocity Agent
      • Solubilizer
      • Speciality Excipient
      • Surfactants
      • Suspension Agent
      • Sustained Release Agent
      • Sweeteners
      • Taste Masking
      • Topical Excipient
      • Viscocity Agent
  • Sources
    • Handbook of Pharmaceutical Excipients – 9th Edition
    • EINECS Numbers
    • Excipient DMF List
    • Excipient cGMP Certification Organisations
    • FDA Inactive Ingredient List
    • FDA GRAS Substances (SCOGS) Database
    • Excipient E-Numbers
    • Whitepapers / Publications
    • Contract Development|Contract Manufacturing
  • Suppliers
    • A-B
      • ADM
      • ARMOR PHARMA
      • Ceolus™ & Celphere™
      • Ashland
      • BASF
      • Beneo – galenIQ
      • Biogrund
      • Budenheim
    • C-G
      • Captisol
      • Croda
      • Cyclolab
      • DFE Pharma
      • DuPont Pharma Solutions
      • Evonik
      • Fuji Chemical Industries
      • Gattefossé
      • Gangwal Healthcare
    • I-O
      • ingredientpharm
      • IOI Oleochemical
      • JRS Pharma
      • Kerry
      • KLK Oleo Life Science
      • Lactalis Ingredients Pharma
      • Lipoid
      • Dr. Paul Lohmann
      • Lubrizol
      • Magnesia
      • MEGGLE Excipients
      • Nagase Viita – Pharmaceutical Ingredients
      • Nordic Bioproducts Group
    • P-Z
      • Pfanstiehl
      • pharm-a-spheres
      • Pharma Line
      • PMC Isochem
      • Roquette Pharma
      • Seppic
      • Shin-Etsu
      • Sigachi Group
      • Südzucker AG
      • VIKRAM THERMO
      • Zerion Pharma
      • ZoomLab® – Your Virtual Pharma Assistant
  • Inquiries
    • Product Inquiry
    • Tailored Tableting Excipients
      • Tailored Film Coating
  • Events
    • Overview Pharmaceutical Webinars
    • Videos CPhI Frankfurt 2025
    • CPhI China 2024
    • ExciPerience – The great excipient event!
  • All4Nutra

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