Unlock Stability: Discover How PureCoat® MPS-D Transforms Moisture-Sensitive Formulations

In the ever-evolving pharmaceutical landscape, ensuring the stability and efficacy of moisture-sensitive and hydrophilic formulations is crucial. That’s where PureCoat® MPS-D comes in – a ready-to-prepare film coating system designed specifically for solid oral dosage forms from Sigachi.

With its unique formulation of HPMC and Diethyl Phthalate, PureCoat® MPS-D not only provides a robust moisture barrier but also enhances the overall stability of your products.

Check out the technical product information from Sigachi to understand how PureCoat® MPS-D can elevate your pharmaceutical formulations!

PureCoat® MPS-D

A Ready-to-prepare film coating systems for moisture-sensitive and hydrophilic solid oral pharmaceutical formulations.

PureCoat® MPS-D offers superior moisture barrier performance for moisture-sensitive and hydrophilic ingredients in solid oral pharmaceutical tablets.

Enhancing Stability in Solid Oral Dosage Forms

PureCoat® MPS-D comprises of polymer, plasticizer, opacifier and anti-tacking agents in pre-optimized quantities.

Why choose PureCoat® MPS-D?

• Low Moisture Uptake
• Superior Moisture Barrier Performance
• Enhanced Stability
• Regulatory Compliance
• Enhanced Aesthetic Appeal
• Versatile Application

Key Benefits

• Lower Moisture Uptake: PureCoat® MPS-D demonstrated significantly lower moisture uptake than Hypromellose-coated and methaacrylate based products under high humidity conditions (75% and 95%)
• Lesser Loss on Drying (LOD): The PureCoat® MPS-D coated specimens showed lesser LOD at 105°C compared to other coatings, indicating superior moisture barrier properties.
• WVTR Performance: Solvent casted films (at << 3 mm thickness) of PureCoat® MPS-D demonstrated significantly lesser WVTR values (about 160 g water/m².d) than Hypromellose- coated (about 900 g water/ m².d) and Methaacrylate based product (≈200 g water/m².d).

See the full technical brochure on “PureCoat® MPS-D” here

(click the picture to download the brochure)

Source: Sigachi, technical brochure “PureCoat® MPS-D”

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