Trehalose

Most of biopharmaceuticals, in their liquid form, are prone to instabilities during storage. In order to improve their stability, lyophilization...

Abstract Background Traumatic brain injury (TBI) is the most common cause of cognitive and behavioral deficits, disability, and mortality worldwide....

A dry powder inhaled liposomal azithromycin formulation was developed for the treatment of chronic respiratory diseases such as cystic fibrosis...

Successful oral delivery of liposomes requires formulations designed to withstand harsh gastrointestinal conditions, e.g., by converting to solid-state followed by...

Spray drying microencapsulation has emerged as a promising technique for producing highly active probiotic powders. The efficient delivery of live...

Over the last 15 years, spray drying (SD), as an alternative to lyophilization, to manufacture and increase the stability of...

Freeze drying is a commonly used method for preserving probiotic bacteria and live biotherapeutic products. Before drying, the bacterial cells...

Abstract Freeze-drying of biopharmaceutical products is the method of choice in order to improve their stability and storage conditions. Such...

Abstract Crystalline carriers such as dextrose, sucrose, galactose, mannitol, sorbitol, and isomalt have been reported to increase the solubility, and...

Abstract Background Process intensification is a major hurdle in pharmaceutical process scale-up. Solvent removal strategies have limited the effectiveness of...