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Topical Excipients as Pharmaceutical Excipients

Jan 26, 2024

Topical excipients play a crucial role in the formulation of pharmaceutical products intended for external use, such as creams, ointments, gels, and transdermal patches. These excipients serve various purposes, including enhancing drug…

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Nanostructured Lipid Carriers for Improved Delivery of Therapeutics via the Oral Route

Nov 22, 2023

Abstract Drug delivery via the oral route has always been challenging for poorly soluble drugs. Acid-induced hydrolysis, enzymatic degradation, and poor mucosal absorbency remain the primary hiccups for effective oral delivery of…

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Enhanced stability and skin permeation of ibuprofen-loaded solid lipid nanoparticles based binary…

Aug 18, 2023

Hypothesis The type of emulsifier selected has an impact on the physicochemical properties of solid lipid nanoparticles (SLNs). This study was designed to compare the effects of emulsifiers on the physicochemical properties and in vitro…

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Innovative Aqueous Nanoemulsion Prepared by Phase Inversion Emulsification with Exceptional…

Jul 18, 2023

Formulating low-solubility or low-permeability drugs is a challenge, particularly with the low administration volumes required in intranasal drug delivery. Nanoemulsions (NE) can solve both issues, but their production and physical…

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Preformulation screening of lipids using solubility parameter concept in conjunction with…

May 17, 2023

Abstract Development of ceftriaxone loaded nanostructured lipid carriers to increase permeability of ceftriaxone across uninflamed meninges after parenteral administration. Lipids were selected by theoretical and experimental techniques…

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Recent Progress of Solid Lipid Nanoparticles and Nanostructured Lipid Carriers as Ocular Drug…

Apr 2, 2023

Abstract Sufficient ocular bioavailability is often considered a challenge by the researchers, due to the complex structure of the eye and its protective physiological mechanisms. In addition, the low viscosity of the eye drops and the…

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The development of a solid lipid nanoparticle (SLN)-based lacticin 3147 hydrogel for the treatment…

Apr 1, 2023

Chronic wounds affect millions of people globally. This number is set to rise with the increasing incidence of antimicrobial-resistant bacterial infections, such as methicillin-resistant Staphylococcus aureus (MRSA), which impair the…

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Engineered Lipid Excellence Quality & Regulatory – IOI Oleo

Feb 23, 2023

See the brochure by IOI Oleo Pharma about their Quality & Regulatory: EXCIPIENTS & ACTIVE PHARMACEUTICAL INGREDIENTS - MADE IN GERMANY Founded in 1905, IOI Oleo’s manufacturing site in Witten has been engaged…

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Engineered Lipid Excellence For Topical Applications – IOI Oleo

Feb 15, 2023

Tried & Trusted, Quality & Innovation With our nature-based excipients you can develop modern pharmaceutical topical formulations that combine functionality, regulatory compliance and a pleasant skin feel. While the advantages of…

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High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand…

Jan 23, 2023

Preclinical development of deuterated pyrazoloquinolinone ligands, promising drug candidates for various neuropsychiatric disorders, was hindered by unusually low solubility in water and oils. DK-I-60-3…

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