Polymeric Amorphous Solid Dispersions of Dasatinib: Formulation and Ecotoxicological Assessment

30. April 2024

Abstract Dasatinib (DAS), a potent anticancer drug, has been subjected to formulation enhancements due to challenges such as significant first-pass...

Transdermal Delivery of Pramipexole Using Microneedle Technology for the Potential Treatment of Parkinson’s Disease

29. April 2024

Parkinson’s disease (PD) is a debilitating neurodegenerative disease primarily impacting neurons responsible for dopamine production within the brain. Pramipexole (PRA)...

Solid self-emulsifying casein carrier for the improvement on the oral bioavailability of simvastatin

28. April 2024

Simvastatin (SV) is a statin drug that can effectively control cholesterol and prevent cardiovascular diseases. However, SV is water-insoluble, and...

The dawning era of oral thin films for nutraceutical delivery: From laboratory to clinic

27. April 2024

Abstract Oral thin films (OTFs) are innovative dosage forms that have gained tremendous attention for the delivery of nutraceuticals. They...

Fig.1 Phase solubility curve of efavirenz with TPGS (0.001-4% range) aqueous solutions

Amorphous – state Characterization and Dissolution Behaviour of Efavirenz – Tocopheryl Polyethylene Glycol Succinate (TPGS)-1000 Solid Dispersions

22. April 2024

ABSTRACT The aim of the present investigation was to enhance the aqueous solubility and dissolution rate of a poorly soluble...

Engineering of Highly Drug Loaded, Free-Flowing Mini-Particles via Tangential Spray Fluid Bed Granulation

10. April 2024

This poster was presented at the PBP World Meeting 2024 by Glatt Pharmaceutical Services with the Utrecht Institute for Pharmaceutical...

The effect of oral trehalose on inflammatory factors, oxidative stress, nutritional and clinical status in patients with head trauma at intensive care unit: A pilot, double-blind, controlled, randomized clinical trial

9. April 2024

Abstract Background Traumatic brain injury (TBI) is the most common cause of cognitive and behavioral deficits, disability, and mortality worldwide....

Selecting the best excipients to optimize drug delivery

Enhancing Drug Efficacy: Gattefossé’s Expertise in Excipient Selection

7. April 2024

About our company The Gattefossé Group is a community of employees, all driven by a dual mission: the performance of...

Self-microemulsifying drug delivery system as carrier for the oral delivery of glimepiride: Formulation development, optimization, in-vitro characterization, stability assessment, ex-vivo permeation, and in-vivo antidiabetic activity in albino mice

5. April 2024

Abstract Aim: The research aimed to design the glimepiride self-micro emulsifying drug delivery system (SMEDDS) for increased oral bioavailability in...

Medication Lubricants for Oral Delivery of Drugs: Oral Processing Reduces Thickness, Changes Characteristics, and Improves Dissolution Profile

5. April 2024

Abstract Swallowing oral solid dosage forms is challenging for those who have medication swallowing difficulties, including patients with dysphagia. One...

Oral Excipients