Rosacea Topical Treatment and Care: From Traditional to New Drug Delivery Systems

7. August 2023

Rosacea is a multifactorial chronic inflammatory dermatosis characterized by flushing, nontransient erythema, papules and pustules, telangiectasia, and phymatous alterations accompanied...

Quality by design (QbD) approach to develop fast-dissolving tablets using melt-dispersion paired with surface-adsorption method: formulation and pharmacokinetics of flurbiprofen melt-dispersion granules

1. August 2023

Developing amorphous solid dispersions with good flow properties is always challenging for formulation scientists to convert into tablets. Hence, the...

Review of industrially recognized polymers and manufacturing processes for amorphous solid dispersion based formulations

24. July 2023

Evolving therapeutic landscape through combinatorial chemistry and high throughput screening have resulted in an increased number of poorly soluble drugs....

Can Continuous Manufacturing of Topical Semisolids by Hot Melt Extrusion Soon Be a Reality?

21. July 2023

For more than five decades, pharmaceutical manufacturers have been relying heavily on batch manufacturing that is a sequential, multistep, laborious,...

Lactose in tablets: functionality, critical material attributes, applications, modifications and co-processed excipients

16. July 2023

Abstract Lactose is one of the most widespread excipients used in the pharmaceutical industry. Because of its water solubility and...

Figure 1. DS using UF and PH Grades of CeolusTM

Study of direct compression coverage in view of design space – Ceolus UF grades

11. July 2023

1. What is the design space? The design space (DS) is a multidimensional combination and interaction of input variables (e.g.,...

Effect of batch-to-batch variation of spray dried lactose on the performance of feeders

9. July 2023

With the emergence of quality by design (QbD), it becomes imperative to gain understanding of the impact of batch-to-batch variability...

Development of Child-Friendly Lisdexamfetamine Chewable Tablets Using Ion Exchange Resin as a Taste-Masking Carrier Based on the Concept of Quality by Design (QbD)

19. June 2023

Taste masking is critical to improving the compliance of pediatric oral dosage forms. However, it is challenging for extremely bitter...

Characterization and Validation of a New 3D Printing Ink for Reducing Therapeutic Gap in Pediatrics through Individualized Medicines

9. June 2023

Abstract 3D printing technology can be used to develop individualized medicines in hospitals and pharmacies, allowing a high degree of...

Transferrin functionalized nanostructured lipid carriers for targeting Rivastigmine and Resveratrol to Alzheimer’s disease: Synthesis, in vitro characterization and brain uptake analysis

19. May 2023

The management of Alzheimer's disease (AD) remains challenging owing to its complex pathophysiology and blood-brain barrier (BBB) restrictions. A rationally...

Quality by Design (QbD)