Daicel

Abstract In this work, concentration prediction models applicable to a very wide range of concentrations for personalized tablet manufacturing were developed using near-infrared (NIR) spectroscopy. Tablet manufacturing experiments were conducted, and NIR spectral data of the tablets were obtained.…
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This year CPHI Europe opens its doors in Barcelona at Fira Barcelona Gran Via. From 24th to 26th October you can have a face-to-face chat with visitors and exhibitors again. As usual, InnoPack, P-MEC, FDF, ICSE and BioProduction will be held together with CPHI. Pharma Excipients gives you an…
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Co-processed excipients may enhance functionality and reduce drawbacks of traditional excipients for the manufacture of tablets on a commercial scale. The following study aimed to characterize a range of co-processed excipients that may prove suitable for dispersible tablet formulations prepared by…
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Therapeutic proteins and peptides (TPPs) are increasingly favoured above small drug molecules due to their high specificity to the site of action and reduced adverse effects resulting in increased use of these agents for medical treatments and therapies. Consequently, there is a need to formulate…
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The formulation development of amorphous solid dispersions (ASDs) towards a patient-friendly oral solid dosage form is proving to be still challenging. To increase patient’s compliance orodispersible tablets (ODTs) can be seen as promising alternative. Two different ASDs were prepared via hot melt…
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Introduction Continuous Manufacturing (CM) is a manufacturing method in which raw materials or blended materials enter the manufacturing process continuously, and products are discharged continuously throughout the duration of the process1). CM can yield required quantities of products with desired…
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CPHI worldwide opens its doors again. This year in Frankfurt at the Messe Frankfurt. In two weeks, from 1st to 3rd November, you can finally have a face-to-face chat with visitors and exhibitors again. As usual, InnoPack, P-MEC, FDF, ICSE and BioProduction will be held together with CPHI. The…
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The paediatric population has always suffered from a lack of medicines tailored to their needs, especially in terms of accurate dosage, stability and acceptability. Orodispersible dosage forms have gone through a resurrection as an alternative to liquid formulations or fractioned solid formulations,…
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Direct compression (DC) is the simplest process to manufacture tablets. The advantage of DC is that the simplicity of the manufacturing process can reduce manufacturing costs and manufacturing time. On the other hand, we often encounter challenges, such as tableting trouble, tablet weight…
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Introduction Direct compression is the simplest tableting method, contributing to both energy savings and cost advantages. However, maintaining content uniformity of active pharmaceutical ingredient (API) in tablets prepared by direct compression can be challenging, as powders with different…
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