Co-processed Excipient for Direct Compression Designed for Orally Disintegrating Tablets
Developing orally disintegrating tablets (ODTs) is a worldwide trend. In recent years, new excipients and excipient blends have enabled manufacturers to produce ODTs using conventional equipment, i.e., blenders and tablet presses. One such product is GRANFILLER-D, a co-processed excipient for direct compression ODTs. ODTs with GRANFILLER-D provide:
- Well balanced properties between tablet hardness and disintegration time
- High dosing capacity of active pharmaceutical ingredients (APIs)
- Good content uniformity of APIs
The following video gives a quick overview of GRANFILLER-D:
ODTs using GRANFILLER-D have extremely rapid disintegration. In traditional ODTs, porous tablets are prepared with low compression force to ensure a water absorption route. However, in OTDs composed of GRANFILLER-D, the granule particles themselves function as the water absorption route.
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Co-processed Excipient for Direct Compression Designed for Orally Disintegrating Tablets