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BASF Poster
Kolliphor® CS 12 and Kolliphor® CS 20 – emulsifiers by BASF
The science behind emulsifier functionality
Emulsifiers are surface-active substances that reduce the interfacial tension between the oil and water phase of an emulsion. Emulsifiers are adsorbed at the interface, creating a film between the immiscible phases, thus preventing the coalescence of…
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Kollidon® 90 Evo – A highly effective water soluble binder with low impurity profile
Join the evolution of the BASF PVP portfolio! Kollidon® 90 Evo combines outstanding purity and innovative packaging.
Kollidon® 90 Evo is a highly effective binder with exceptional purity
Very low impurity profile, e.g., 2-pyrrolidone, aldehydes and hydrazine
Broad range of applications…
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Soluplus® as Promising Polymer for Topical Film Forming Solid Solutions of Betamethasone…
This poster was presented at the PBP World Meeting 2024 in Vienna:
BACKGROUND & INTRODUCTION
Topical film-forming solutions (FFSs) represent an innovative form of sustained release dermatological dosage forms. They can be applied to the skin as solutions, gels or sprays. After evaporation of…
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Kollicoat® Smartseal combines an effective taste-masking functionality with efficient processing
Kollicoat® Smartseal 30 D and Kollicoat® Smartseal 100 P can help formulators tackle challenges when handling bitter active ingredients. It offers superior protection from unpleasant drug taste for minitablets, pellets, particles, and granules used in orally disintegrating dosage forms, improving…
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Investigating the influence of various plasticiser on the properties of Kollicoat® SR 30 D based…
INTRODUCTION
Plasticiser play a decisive role in the application of functional films, especially, if an aqueous dispersion containing a water insoluble polymer is used. For the water insoluble sustained release film forming polymer PVAc, both elongation at break and minimum film forming temperature…
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Comparing Different Moisture Protective Instant Release Coatings for Solid Oral Dosage Forms
Introduction: Drug stability and shelf life are main targets of current pharmaceutical development as many active ingredients are highly moisture sensitive. Instead of using impermeable and expensive packaging materials it appears advisable to test moisture protective instant release film coatings.…
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Colouring Orally Dispersible Tablets
Delivering active ingredients via orally dispersible tablets (ODTs) is a recent trend in the pharmaceutical industry. Due to the easy and fast application, patient’s compliance is high for this kind of dosage form. To ensure a fast drug release, ODTs are typically not coated.
Nevertheless, a…
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Characterization Requirements for New Excipients
Novel excipients can play a major role in innovation processes, but physicochemical properties, performance and safety must be adequately demonstrated. Characterization requirements for novel excipients are discussed and illustrated with two examples, polyethyleneglycol-polyvinyl caprolactam…
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Expanding the toolbox of surfactants available for biologics formulations with Kolliphor® HS 15 and…
The purpose of this study was to evaluate the performance of the surfactants Polyoxyl 15 Hydroxystearate (Kolliphor® HS 15) and Polyoxyl-35-castor oil (Kolliphor® ELP) in stabilizing proteins formulations. Surfactants are an essential component of biologics formulations, as they stabilize protein…
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Taste Masking of Drug Layered Pellets with the Kollicoat® Smartseal 100P
Taste-masking has proven to be a useful technique to improve patient compliance of oral dosages having bitter actives, especially for pediatric and geriatric products. Kollicoat® Smartseal 100P, a spray dried powder of methyl methacrylate-diethylaminoethyl methacrylate copolymer is an excellent…
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