Vitamin E TPGS

Abstract Polyethoxylated (PEO)-based nonionic surfactants, such as D-α-Tocopheryl polyethylene glycol succinate (TPGS), offer significant advantages in drug delivery due to...

Abstract Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer lacking estrogen receptors, progesterone receptors, and HER2 expression,...

Abstract Aim Proteolysis targeting chimeras (PROTACs) exhibit a unique and promising pharmacology. However, this comes with molecular properties exceeding the...

Abstract Given the recurrent waves of COVID-19 and the emergence of new viral infections, optimizing the potential of remdesivir as...

Abstract Lung cancer, particularly NSCLC, poses a major therapeutic challenge due to drug resistance and the poor aqueous solubility of...

Abstract Background: D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS), an amphiphilic derivative of natural vitamin E, functions as both a drug efflux...

Abstract This study investigated the influence of solvent casting and hot-melt extrusion manufacturing methods on the physical, chemical, and functional...

Abstract Prostate cancer is the most common malignancy in men worldwide and docetaxel (DTX) is the treatment of choice. However,...

Abstract Background/Objectives: Curcumin (CUR) is a natural compound with notable antitumor properties but faces limitations in topical applications due to...

Abstract The current study includes the design of soluplus stabilized, lipid-coated, and fucoidan-oleylamine conjugate modified paclitaxel nanocrystals. The nanocrystals (Lipid-NCs)...