Development of nanoemulsion loaded acyclovir nanogel for transdermal delivery and its evaluation

1. January 2024

Abstract Acyclovir (ACV) is an antiviral drug that is primarily used to treat herpes zoster virus (HSV) infections. HSV infections...

Preparation, optimization and evaluation of Osthole transdermal therapeutic system

30. December 2023

In the current study, the solubility and permeability of Osthole-loaded microemulsion were enhanced, which increased bioavailability. In addition, Carbomer 940...

Preparation of Curcumin Nanostructured Lipid Carriers (NLCs) using emulsion-evaporation-solidification method. Created with BioRender.com

Curcumin-infused nanostructured lipid carriers: a promising strategy for enhancing skin regeneration and combating microbial infection

2. November 2023

Abstract Background Curcumin is a biomolecule that can be extracted from the Curcuma longa that has been shown to have the potential...

Preparation and Characterization of an Antiviral Gel

27. October 2023

ABSTRACT The study was to develop an antiviral gel for topical application. The topical application of drug has many advantages...

QbD Design, Formulation, Optimization and Evaluation of Trans-Tympanic Reverse Gelatination Gel of Norfloxacin: Investigating Gene-Gene Interactions to Enhance Therapeutic Efficacy

23. August 2023

Traditional otic drug delivery methods lack controlled release capabilities, making reverse gelatination gels a promising alternative. Reverse gelatination gels are...

Nanostructured Lipid Carriers to Enhance the Bioavailability and Solubility of Ranolazine: Statistical Optimization and Pharmacological Evaluations

19. August 2023

Chronic stable angina pectoris is the primary indication for ranolazine (RZ), an anti-anginal drug. The drug has an anti-ischemic action...

Topical delivery systems containing clotrimazole for the management of candidiasis: effect of different excipients and enhanced antifungal activity of nanovesicles

13. August 2023

WHO classified Candida albicans as one of the four critical priority fungi for public health worldwide in 2022. Conventional topical formulations commercially...

Beta Caryophyllene-Loaded Nanostructured Lipid Carriers for Topical Management of Skin Disorders: Statistical Optimization, In Vitro and Dermatokinetic Evaluation

20. July 2023

This work aimed to overcome the disadvantages of the oral administration of beta-caryophyllene and boost efficiency by developing a nanostructured...

Hot-melt extruded in situ gelling systems (MeltDrops Technology): Formulation development, in silico modelling and in vivo studies

21. May 2023

In situ gelling systems (ISGS) can prolong retention time and bioavailability of ophthalmic solutions. The complexity and cost of ISGS avert...

Emulsion-Based Gel Loaded with Ibuprofen and Its Derivatives

18. May 2023

The aim of this study was to evaluate the effect of vehicle and chemical modifications of the structure of active...

Carbomer