Resins That Allow Distinctive Drug Delivery Solutions – POLYOX™ product information
POLYOX™ resins are nonionic poly (ethylene oxide) polymers. They are white to off-white, free-flowing hydrophilic powders supplied in a wide variety of viscosity grades corresponding to approximate molecular weight, ranging from 100,000 to 7,000,000 daltons. POLYOX™ polymers possess thermoplastic properties, are fast-hydrating and very quickly form hydrogels. They are essentially tasteless, colorless, nonionic and non-caloric. Their unusual combination of properties makes them useful in a surprisingly broad array of pharmaceutical formulations such as controlled release formulations, tablet binding and mucosal bioadhesives.
Benefits
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- High solubility in water and polar solvents
- Very fast hydration, rapid swelling and hydrogel formation
- Molecular weights ranging from 100,000 to 7,000,000 daltons
- Hydrogen bonding functionality and good biocompatibility
- Thermoplastic polymer with low melting point of ~ 65°C
- Does not show a strong pH response due to their nonionic nature
- Tasteless, colorless, nonionic and non-caloric